Title:
【発明の名称】INGAPの大量発現
Document Type and Number:
Japanese Patent JP2001502916
Kind Code:
A
Abstract:
Removal of the nucleotide sequence encoding the signal peptide from the INGAP coding sequence allows cultured cells to express substantial amounts of INGAP activity. Previous attempts have provided only low yields of INGAP, possibly because the signal sequence of INGAP is toxic to the cells.
Inventors:
Vinnick, Aaron Eye
Pittinger, Gary Eye
Raffaeloff, Ronito
Barlow, Scott W
Pittinger, Gary Eye
Raffaeloff, Ronito
Barlow, Scott W
Application Number:
JP52066598A
Publication Date:
March 06, 2001
Filing Date:
October 30, 1997
Export Citation:
Assignee:
Eastern Virginia Medical School of the Medical College of Hampton Rose
International Classes:
C07K1/22; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12N15/09; (IPC1-7): C12N15/09; C07K1/22; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)