Title:
【発明の名称】N-(5-アミノ-2-シアノ-4-フルオロ-フェニル)-スルホンアミド類の製造方法および新規な中間体生成物
Document Type and Number:
Japanese Patent JP2001510823
Kind Code:
A
Abstract:
The invention relates to a process for preparing N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides in which, in a first step, 2-amino-4,5-difluoro-benzonitrile is reacted with sulphonyl halides in the presence of an acid acceptor and in the presence of a diluent at temperatures between 0° C. and 150° C. and, in a second step, the N-(2-cyano-4,5-difluoro-phenyl)-sulphon-amides and/or N-(2-cyano-4,5-difluoro-phenyl)-sulphonamides obtained in the first step are as pure substances or as mixtures with ammonia in the presence of a diluent reacted at a temperature between 100° C. and 200° C. The invention furthermore relates to novel intermediates of the process.
Inventors:
Hutperz, Ahim
Drew's, Mark Wilhelm
Eldman, David
Ranchiyu, Reinhard
Drew's, Mark Wilhelm
Eldman, David
Ranchiyu, Reinhard
Application Number:
JP2000504099A
Publication Date:
August 07, 2001
Filing Date:
July 13, 1998
Export Citation:
Assignee:
Bayer Actien Gezershyaft
International Classes:
C07C211/52; C07C253/30; C07C255/58; C07C303/38; C07C303/40; C07C311/08; C07C311/48; (IPC1-7): C07C303/38; C07C253/30; C07C255/58; C07C303/40; C07C311/08; C07C311/48
Attorney, Agent or Firm:
Heiyoshi Odashima (1 person outside)