Title:
【発明の名称】ミクロソーム・トリグリセリド転移たんぱくの環式ホスホネートエステル抑制剤および抑制方法
Document Type and Number:
Japanese Patent JP2001521001
Kind Code:
A
Abstract:
Novel cyclic phosphonate ester inhibitors of MTP are provided which have structure (I) wherein R<2>, L<2>, A, B, L<1>, R<1> and R<5a> are as set out herein. These compounds are useful in lowering serum cholesterol and triglycerides.
Inventors:
Richard B. Sarsky
Application Number:
JP2000517722A
Publication Date:
November 06, 2001
Filing Date:
October 14, 1998
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/675; A61K31/66; A61P3/04; A61P3/06; A61P9/10; A61P43/00; C07F9/6571; C07F9/6574; (IPC1-7): A61K31/675; A61K31/66; A61P3/04; A61P3/06; A61P9/10; A61P43/00; C07F9/6574
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)