Title:
【発明の名称】疎水性テトラサイクリンによるセリンプロテイナーゼ阻害活性
Document Type and Number:
Japanese Patent JP2001524948
Kind Code:
A
Abstract:
A method for inhibiting the activity of serine proteinase in biological systems includes administering to the system a serine proteinase inhibitory amount of a hydrophobic 4-de(dimethylamino)tetracycline. The method reduces tissue destruction during inflammation resulting from the activity of human leukocyte elastase. The method is used for pharmaceutical and cosmetic purposes.
Inventors:
Simon Sanford Earl
Romer Elizabeth Jay
Go Love Lone M
Ramamarty Nungavaram S
Romer Elizabeth Jay
Go Love Lone M
Ramamarty Nungavaram S
Application Number:
JP53959398A
Publication Date:
December 04, 2001
Filing Date:
February 26, 1998
Export Citation:
Assignee:
The Research Foundation of State University of New York
International Classes:
A61K31/65; A61P11/00; A61P13/12; A61P29/00; A61P43/00; (IPC1-7): A61K31/65; A61P11/00; A61P13/12; A61P43/00
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)