Title:
【発明の名称】チアゾフリンおよびその他のC-ヌクレオシドを作製する方法
Document Type and Number:
Japanese Patent JP2002501546
Kind Code:
A
Abstract:
C-nucleosides are synthesized by a method in which a sugar is derivatized in a single step to provide a heterocycle at the C1 position, and then the heterocycle is aromatized in another single step. In one class of preferred embodiments a cyano sugar is converted into thiocarboxamide, and subsequently condensed to form an azole ring. In a second class of preferred embodiments a cyano sugar is condensed with an amino acid to provide the azole ring. In a third class of preferred embodiments a halo sugar is condensed with a preformed heterocycle to provide the azole ring.
Inventors:
Rama Sammy, Kanda Sammy
Bandar, Large Yanyans
Abeletto, Devlon
Bandar, Large Yanyans
Abeletto, Devlon
Application Number:
JP50579799A
Publication Date:
January 15, 2002
Filing Date:
June 25, 1998
Export Citation:
Assignee:
ICN Pharmacy Youthicals Incorporated
International Classes:
A61K31/427; A61P35/02; C07D417/04; C07H7/06; C07H9/02; C07H19/04; C07H1/00; C07H3/00; (IPC1-7): C07D417/04; A61K31/427; A61P35/02
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)