Title:
【発明の名称】安定なインスリン製剤
Document Type and Number:
Japanese Patent JP2002504908
Kind Code:
A
Abstract:
The present invention provides a monomeric insulin analog formulation stabilized against aggregation in which the buffering agent is either TRIS or arginine. The stable formulations of the present invention are useful for treating diabetes, and are particularly advantageous in treatment regimes requiring lengthy chemical and physical stability, such as, in continuous infusion systems.
Inventors:
Defelipis, Michael Rosario
Dobbins, Michael Allen
Frank, Bruce Hill
Li, Shun
Rivern, Dawn Marie
Dobbins, Michael Allen
Frank, Bruce Hill
Li, Shun
Rivern, Dawn Marie
Application Number:
JP50323799A
Publication Date:
February 12, 2002
Filing Date:
June 11, 1998
Export Citation:
Assignee:
ELI LILLY AND COMPANY
International Classes:
A61K38/28; A61K47/02; A61K47/10; A61K47/16; A61K9/08; A61K47/18; A61P3/10; (IPC1-7): A61K38/28; A61K9/08; A61K47/16; A61P3/10
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)