Title:
【発明の名称】培養基上に流体試料をデポジットし、整列したアレイを形成し、デポジットされたアレイを分析するための技術
Document Type and Number:
Japanese Patent JP2002509274
Kind Code:
A
Abstract:
A fluid deposit assembly mounted on a carrier for depositing minute drops of fluid at selected locations upon a substrate, comprising a deposit element having an exposed tip of diameter of 0.3 mm or less constructed and arranged to carry and deposit drops of fluid upon the substrate, stable lateral reference surfaces or surface portions exposed for engagement by the deposit element, the surfaces or surface portions being constructed and arranged to prevent X, Y displacement of the deposit element relative to the carrier when the deposit element is urged thereagainst and design for urging the deposit element against the reference surfaces or surface portions at least at the time that the deposit element approaches a substrate to deposit a fluid drop. The reference surfaces or surface portions and the design for urging are cooperating to precisely position the deposit tip in a precisely desired position as it contacts the substrate.The deposit element is shown as the tip of an axially moveable pin. The reference surface portion is shown, among others, as a surface of revolution whose axis is disposed at a predetermined position relative to the carrier. A mobile supply in the form of a multiwell plate is moved under computer control to be a close companion of the deposit device, enabling rapid deposit action and avoidance of evaporative effects that can alter the consistency of dots in the array being formed. The device can deposit one dot on top of another from fluid in a mobile multiwell plate that moves to be close to the deposit device.
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Inventors:
James W. Overbeck
Peter ti flowers
Gene I Montagu
Miles El Mace
Peter Honkanen
Peter ti flowers
Gene I Montagu
Miles El Mace
Peter Honkanen
Application Number:
JP2000540421A
Publication Date:
March 26, 2002
Filing Date:
January 13, 1999
Export Citation:
Assignee:
Genetic Micro Systems Incorporated
International Classes:
G01N37/00; B01J4/00; B01J19/00; B01L3/02; C12M1/00; C12N15/09; G01N21/64; G01N35/10; G02B21/00; G02B21/34; B01L99/00; C40B60/14; (IPC1-7): G02B21/34; B01J4/00; C12M1/00; C12N15/09; G01N35/10; G01N37/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)