Title:
【発明の名称】外陰膣炎および膣症を局所的に治療するための医薬品イミダゾールの併用
Document Type and Number:
Japanese Patent JP2002512961
Kind Code:
A
Abstract:
The invention concerns a pharmaceutical composition comprising a combination of at least two imidazole derivatives having reinforcing synergy against germs which cause infectious vulvovaginitis and vaginosis and selected from the group comprising metronidazole, econazole, miconazole, clotrimazole, terconazole, bifonazole, cloconazole, isoconazole, oxiconazole, sulconazole, tioconazole and their salts, preferably metronidazole combined with econazole. The composition is advantageously in galenic form of a hard or soft capsule having an solid hard or soft outer envelope containing gelatine, enclosing an internal non-aqueous lipophilic liquid or semi-liquid phase wherein the imidazole derivatives are suspended in a lipophilic agent, a water-dispersible agent and a bioadhesive agent.
Inventors:
Cignine, Maygnanto
Vieirado-Baron, Corrine
Verdiere, Stephanie
Vieirado-Baron, Corrine
Verdiere, Stephanie
Application Number:
JP2000545531A
Publication Date:
May 08, 2002
Filing Date:
April 23, 1999
Export Citation:
Assignee:
Laboratore Inotera, Societe Anonymous
International Classes:
A61K9/48; A61K31/415; A61K31/4164; A61P15/02; (IPC1-7): A61K31/4164; A61K9/48; A61P15/02
Attorney, Agent or Firm:
Masao Okabe (11 others)