Title:
【発明の名称】新規ポリメチリデンマロネート微小球、調製方法、及び、それらを含む医薬組成物
Document Type and Number:
Japanese Patent JP2002513042
Kind Code:
A
Abstract:
The invention concerns novel microspheres particularly useful in pharmaceutics as particulate vectors for carrying biologically active substances, in particular hydrophilic substances, for oral administration. The invention is characterised in that said microspheres consist of a support material continuous lattice wherein is optionally dispersed a substance, said support material containing at least 70 wt. % of a homopolymer consisting of recurrent units corresponding to general formula (I):wherein: R1 represents an alkyl group containing 1 to 6 carbon atoms or a (CH2)m-COOR3 group wherein m is an integer ranging between 1 and 5 and R3 represents an alkyl group having 1 to 6 carbon atoms; R2 represents an alkyl group having 1 to 6 carbon atoms; and n is an integer ranging between 1 and 5. The invention is useful in pharmaceutics.
Inventors:
Nicole Bru-Manier
Catherine Le Bisage
Elias Fatal
Patrick Couvroll
Pascal Breton
Catherine Le Bisage
Elias Fatal
Patrick Couvroll
Pascal Breton
Application Number:
JP2000545509A
Publication Date:
May 08, 2002
Filing Date:
April 28, 1999
Export Citation:
Assignee:
Vilsol
International Classes:
A61K9/16; A61K9/50; A61K38/00; A61K47/32; A61K47/34; C07K17/08; C08F122/14; C08J3/14; (IPC1-7): C08F122/14; A61K9/16; A61K9/50; A61K38/00; A61K47/32; A61K47/34
Attorney, Agent or Firm:
Yasuo Yasutomi (2 outside)