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Title:
【発明の名称】酸化窒素シンターゼ阻害剤
Document Type and Number:
Japanese Patent JP2002516901
Kind Code:
A
Abstract:
The present invention relates to novel amidino compounds of formula (I),or a salt, solvate, or physiologically functional derivative thereof;wherein R1 is selected from C1-4 alkyl, C3-4 cycloalkyl, C1-4 hydroxyalkyl, and C1-4 haloalkyl; to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.

Inventors:
Paul, John, Beswick
Servus, Clean South
Robert, John, Young
Application Number:
JP2000552087A
Publication Date:
June 11, 2002
Filing Date:
May 27, 1999
Export Citation:
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Assignee:
GLAXO GROUP LIMITED
International Classes:
A61K31/13; A61K31/155; A61K31/195; A61K31/197; A61K31/198; A61P1/04; A61P1/00; A61P9/00; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P19/02; A61P25/00; A61P25/06; A61P29/00; A61P31/04; A61P37/00; A61P43/00; C07C61/04; C07C321/00; C07C323/00; C07C323/58; A61K; C07C; (IPC1-7): C07C323/58; A61K31/198; A61P1/00; A61P11/06; A61P19/02; A61P25/06; A61P43/00
Attorney, Agent or Firm:
Kazuo Sato (3 others)