Title:
【発明の名称】ワクチン
Document Type and Number:
Japanese Patent JP2002517218
Kind Code:
A
Abstract:
This invention relates to three newly-identified, distinct groups of antigenic peptides [LB1(f) peptides] from the same region of the P5-like fimbrin protein discovered using sequence data from the fimbrin protein of many Haemophilus influenzae strains. The invention additionally provides chimeric polypeptides that carry one or more representatives of such peptides from different groups and which induce an immunogenic response in animals to Haemophilus influenzae. The peptides and polypeptides of the invention will be useful in vaccine compositions which provide protection against a wide range of H. influenzae strains.
Inventors:
Lauren Oh Bakalets
Joseph Cohen
Guy Duquesnu
Eve robe
Joseph Cohen
Guy Duquesnu
Eve robe
Application Number:
JP2000553135A
Publication Date:
June 18, 2002
Filing Date:
May 28, 1999
Export Citation:
Assignee:
SmithKline Beecham Biologicals (Societe Anonym)
Ohio State University Research Foundation
Ohio State University Research Foundation
International Classes:
A61K39/102; A61K39/395; A61P27/16; A61P31/04; A61P31/16; C07K14/195; C07K14/285; C07K16/12; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12Q1/04; C12Q1/68; G01N33/53; G01N33/569; A61K39/00; C12R1/21; (IPC1-7): C12N15/09; A61K39/102; A61K39/395; A61P27/16; A61P31/16; C07K14/195; C07K16/12; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/04; C12Q1/68; G01N33/53
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)