Title:
【発明の名称】メタロプロテイナーゼ阻害剤としての環式ヒドロキサム酸類
Document Type and Number:
Japanese Patent JP2002518368
Kind Code:
A
Abstract:
The present application describes novel cyclic hydroxamic acids of formula I:or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NR, and S(O)p, and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease inhibitors.
Inventors:
Chiu-Bio Shwe
Karl P. Decicco
Xiaohaaa
Karl P. Decicco
Xiaohaaa
Application Number:
JP2000554694A
Publication Date:
June 25, 2002
Filing Date:
June 17, 1999
Export Citation:
Assignee:
DuPont Pharmaceuticals Company
International Classes:
A61K31/167; A61K31/4406; A61K31/4418; A61K31/4427; A61K31/443; A61K31/4433; A61K31/445; A61K31/4465; A61K31/45; A61K31/451; A61K31/4545; A61K31/47; A61K31/4709; A61P1/02; A61P7/02; A61P7/04; A61P9/02; A61P9/04; A61P17/04; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P27/02; A61P29/00; A61P31/04; A61P33/06; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07C259/08; C07D211/16; C07D211/22; C07D211/60; C07D211/76; C07D213/30; C07D213/40; C07D213/61; C07D213/65; C07D215/20; C07D215/22; C07D215/233; C07D401/12; C07D401/14; C07D405/14; C07D409/14; C07D417/14; (IPC1-7): C07C259/08; A61K31/167; A61K31/445; A61K31/45; A61K31/4545; A61K31/47; A61K31/4709; A61P1/02; A61P7/02; A61P7/04; A61P9/02; A61P9/04; A61P17/04; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P27/02; A61P29/00; A61P31/04; A61P33/06; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D211/16; C07D211/22; C07D211/60; C07D211/76; C07D213/30; C07D213/61; C07D213/65; C07D215/20; C07D215/22; C07D401/12; C07D401/14; C07D405/14; C07D409/14; C07D417/14
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)