Title:
【発明の名称】少量のトリスルフィドを有する組換えペプチドの製造法
Document Type and Number:
Japanese Patent JP2002520332
Kind Code:
A
Abstract:
Methods for the production of recombinant peptides comprise fermenting cells to produce recombinant peptides. A metal salt is added to a concentrate of the fermented cells after the fermentation step, prior to peptide isolation, thereby reducing the amount of trifulsides formed in the production of the recombinant peptide. In one embodiment, the recombinant peptide is recombinant growth hormone.
Inventors:
Hemmendorf, Barblue
Andreas, Castan
Petition, Andilles
Andreas, Castan
Petition, Andilles
Application Number:
JP2000559129A
Publication Date:
July 09, 2002
Filing Date:
July 05, 1999
Export Citation:
Assignee:
Pharmacia Actie Borrag
International Classes:
C07K1/113; C07K14/61; (IPC1-7): C07K1/113; C07K14/61
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)