Title:
【発明の名称】ラクトシルセラミドによって調節される病態を治療する方法
Document Type and Number:
Japanese Patent JP2002521435
Kind Code:
A
Abstract:
The present invention includes methods for treatment and prophylaxis of conditions associated with lactosylceramide. The methods generally provide for administration to a mammal, particularly a human, of a therapeutically effective amount of a compound that increases enzymatic activity of UDPGal:GlcCerbeta1->4 galactosylceramide (GalT-2). In vitro and in vivo assays for detecting compounds with therapeutic capacity to modulate GalT-2 are also provided.
Inventors:
Chatterjee Sablot
Application Number:
JP2000562000A
Publication Date:
July 16, 2002
Filing Date:
July 22, 1999
Export Citation:
Assignee:
JOHNS HOPKINS UNIVERSITY
International Classes:
C07D295/12; A61K31/00; A61K31/16; A61K31/40; A61K31/4453; A61K31/5375; A61K38/00; A61K38/17; A61K38/18; A61K38/19; A61K38/22; A61K45/00; A61K45/06; A61P9/10; A61P17/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P43/00; (IPC1-7): A61K45/00; A61K31/40; A61K31/4453; A61K31/5375; A61K38/00; A61K38/22; A61K45/06; A61P9/10; A61P17/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P43/00
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)