Title:
【発明の名称】オキサジアゾール化合物及び活性剤をデリバリーするための組成物
Document Type and Number:
Japanese Patent JP2002536400
Kind Code:
A
Abstract:
Oxadiazole compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
More Like This:
Inventors:
David Gushnadner
Application Number:
JP2000598141A
Publication Date:
October 29, 2002
Filing Date:
February 11, 2000
Export Citation:
Assignee:
Emisfair Technologies Inc.
International Classes:
A61K31/353; A61K31/70; A61K31/715; A61K38/00; A61K38/04; A61K38/095; A61K38/21; A61K38/22; A61K38/23; A61K38/27; A61K38/28; A61K38/55; A61K45/00; A61K45/06; A61K47/22; A61P5/22; C07D271/10; (IPC1-7): C07D271/10; A61K31/353; A61K31/70; A61K31/715; A61K38/00; A61K38/04; A61K38/11; A61K38/21; A61K38/22; A61K38/27; A61K38/28; A61K38/55; A61K45/00; A61K47/22; A61P5/22
Domestic Patent References:
| JPS4220057B1 | ||||
| JPH10324695A | 1998-12-08 | |||
| JPH06107615A | 1994-04-19 | |||
| JPS5363395A | 1978-06-06 | |||
| JPS5182393A | 1976-07-19 | |||
| JPH10509433A | 1998-09-14 | |||
| JPH072851A | 1995-01-06 | |||
| JPS59101494A | 1984-06-12 |
Foreign References:
| US5668159A | 1997-09-16 | |||
| US2765304A | 1956-10-02 | |||
| US3964896A | 1976-06-22 |
Other References:
JPN7010002191, ルーマニア特許第６４９０２号明細書
JPN6010040337, Ｌｉｎａ Ｍｅｈｔａ ｅｔ ａｌ．, "Ｓｔｕｄｉｅｓ ｏｎ ｕｒｅａｓ． Ｐａｒｔ Ｉ． Ｐｒｅｐａｒａｔｉｏｎ ａｎｄ ａｎｔｉｍｉｃｒｏｂｉａｌ ａｃｔｉｖｉｔｙ ｏｆ Ｎ’−ａｒｙｌ−Ｎ３−２−ｐ−ｃｈｌｏｒｏｐｈｅｎｙｌ−１，３，", Ｊｏｕｒｎａｌ ｏｆ ｔｈｅ Ｉｎｄｉａｎ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ, １９８８， ６５（７）， ｐ．５２１−５２２
JPN6010040338, Ｍａｓａｈｉｋｏ Ｔａｋａｈａｓｈｉ ｅｔ ａｌ．, "Ｓｙｎｔｈｅｓｉｓ ｏｆ １，３，４−ｏｘａｄｉａｚｏｌｏ［３，２−ｂ］ｉｓｏｑｕｉｎｏｌｉｎｅ ａｎｄ １，３，４−ｔｈｉａｄｉａｚｏｌｏ［３，２−ｂ］ｉｓｏｑｕｉｎｏｌｉｎｅ ｄｅｒｉｖａｔｉｖｅ", Ｂｕｌｌｅｔｉｎ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ ｏｆ Ｊａｐａｎ, １９７５， ４８（１０）， ｐ．２９１５−２９１７
JPN6010040340, Ｆｒａｎｋｌｉｎ Ｗ． Ｓｈｏｒｔ ｅｔ ａｌ．, "Ｓｙｎｔｈｅｓｉｓ ｏｆ ５−ａｒｙｌ−２−ｏｘａｚｏｌｅｐｒｏｐｉｏｎｉｃ ａｃｉｄｓ ａｎｄ ａｎａｌｏｇｓ． Ａｎｔｉ−ｉｎｆｌａｍｍａｔｏｒｙ ａｇｅｎｔｓ", Ｊｏｕｒｎａｌ ｏｆ Ｈｅｔｅｒｏｃｙｃｌｉｃ Ｃｈｅｍｉｓｔｒｙ, １９６９， ６（５）， ｐ．７０７−７１２
JPN6010040342, Ｒ．Ｒａａｐ, "Ｓｏｍｅ ｓｙｎｔｈｅｓｅｓ ｗｉｔｈ ｄｉｍｅｔｈｙｌ ｍｏｎｏｔｈｉｏｎｅｍａｌｏｎａｔｅ", Ｃａｎａｄｉａ Ｊｏｕｒｎａｌ ｏｆ Ｃｈｅｍｉｓｔｒｙ, １９６８， ４６， ｐ．２２５５−２２６１
JPN6010040344, Ｊａｃｑｕｅｓ Ｍａｉｌｌａｒｄ ｅｔ ａｌ．, "Ａｎｔｉ−ｉｎｆｌａｍｍａｔｏｉｒｅｓ ｄｅｒｉｖｅｓ ｄｅ ｌ’ａｃｉｄｅ ｐｈｅｎｙｌａｃｅｔｉｑｕｅ", Ｃｈｉｍｉｅ Ｔｈｅｒａｐｅｕｔｉｑｕｅ, １９７３， ４， ｐ．４８７−４９４
JPN6010040347, Ｊｅａｎ Ｇｏｄｉｎ ｅｔ ａｌ．, "Ｃｙｃｌｉｃ ｈｙｄｒａｚｉｄｅｓ． Ｉ， Ｒｅａｃｔｉｏｎ ｗｉｔｈ ｄｉｃａｒｂｏｘｙｌｉｃ ａｃｉ ｃｈｌｏｒｉｄｅｓ", Ｂｕｌｌｅｔｉｎ ｄｅ ｌａ Ｓｏｃｉｅｔｅ Ｃｈｉｍｉｑｕｅ ｄｅ Ｆｒａｎｃｅ, １９６８， （１０）， ｐ．４２１０−４２２１
JPN6010040349, Ｋ． Ｓａｏｔｏｍｅ ｅｔ ａｌ．, "Ｔｈｅ ｓｙｎｔｈｅｓｉｓ ｏｆ ｄｉｃａｒｂｏｘｙｌｉｃ ａｃｉｄｓ ｃｏｎｔａｉｎｉｎｇ ｏｘａｄｉａｚｏｌｅ ｒｉｎｇｓ ａｎｄ ｐｏｌｙａｍｉｄｅｓ ｄｅｒｉｖｅｄ ｆｒｏｍ ｔｈｅｍ", Ｍａｋｒｏｍｏｌｅｋｕｌａｒｅ Ｃｈｅｍｉｅ, １９６７， １００， ｐ．９１−９９
JPN6010040337, Ｌｉｎａ Ｍｅｈｔａ ｅｔ ａｌ．, "Ｓｔｕｄｉｅｓ ｏｎ ｕｒｅａｓ． Ｐａｒｔ Ｉ． Ｐｒｅｐａｒａｔｉｏｎ ａｎｄ ａｎｔｉｍｉｃｒｏｂｉａｌ ａｃｔｉｖｉｔｙ ｏｆ Ｎ’−ａｒｙｌ−Ｎ３−２−ｐ−ｃｈｌｏｒｏｐｈｅｎｙｌ−１，３，", Ｊｏｕｒｎａｌ ｏｆ ｔｈｅ Ｉｎｄｉａｎ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ, １９８８， ６５（７）， ｐ．５２１−５２２
JPN6010040338, Ｍａｓａｈｉｋｏ Ｔａｋａｈａｓｈｉ ｅｔ ａｌ．, "Ｓｙｎｔｈｅｓｉｓ ｏｆ １，３，４−ｏｘａｄｉａｚｏｌｏ［３，２−ｂ］ｉｓｏｑｕｉｎｏｌｉｎｅ ａｎｄ １，３，４−ｔｈｉａｄｉａｚｏｌｏ［３，２−ｂ］ｉｓｏｑｕｉｎｏｌｉｎｅ ｄｅｒｉｖａｔｉｖｅ", Ｂｕｌｌｅｔｉｎ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ ｏｆ Ｊａｐａｎ, １９７５， ４８（１０）， ｐ．２９１５−２９１７
JPN6010040340, Ｆｒａｎｋｌｉｎ Ｗ． Ｓｈｏｒｔ ｅｔ ａｌ．, "Ｓｙｎｔｈｅｓｉｓ ｏｆ ５−ａｒｙｌ−２−ｏｘａｚｏｌｅｐｒｏｐｉｏｎｉｃ ａｃｉｄｓ ａｎｄ ａｎａｌｏｇｓ． Ａｎｔｉ−ｉｎｆｌａｍｍａｔｏｒｙ ａｇｅｎｔｓ", Ｊｏｕｒｎａｌ ｏｆ Ｈｅｔｅｒｏｃｙｃｌｉｃ Ｃｈｅｍｉｓｔｒｙ, １９６９， ６（５）， ｐ．７０７−７１２
JPN6010040342, Ｒ．Ｒａａｐ, "Ｓｏｍｅ ｓｙｎｔｈｅｓｅｓ ｗｉｔｈ ｄｉｍｅｔｈｙｌ ｍｏｎｏｔｈｉｏｎｅｍａｌｏｎａｔｅ", Ｃａｎａｄｉａ Ｊｏｕｒｎａｌ ｏｆ Ｃｈｅｍｉｓｔｒｙ, １９６８， ４６， ｐ．２２５５−２２６１
JPN6010040344, Ｊａｃｑｕｅｓ Ｍａｉｌｌａｒｄ ｅｔ ａｌ．, "Ａｎｔｉ−ｉｎｆｌａｍｍａｔｏｉｒｅｓ ｄｅｒｉｖｅｓ ｄｅ ｌ’ａｃｉｄｅ ｐｈｅｎｙｌａｃｅｔｉｑｕｅ", Ｃｈｉｍｉｅ Ｔｈｅｒａｐｅｕｔｉｑｕｅ, １９７３， ４， ｐ．４８７−４９４
JPN6010040347, Ｊｅａｎ Ｇｏｄｉｎ ｅｔ ａｌ．, "Ｃｙｃｌｉｃ ｈｙｄｒａｚｉｄｅｓ． Ｉ， Ｒｅａｃｔｉｏｎ ｗｉｔｈ ｄｉｃａｒｂｏｘｙｌｉｃ ａｃｉ ｃｈｌｏｒｉｄｅｓ", Ｂｕｌｌｅｔｉｎ ｄｅ ｌａ Ｓｏｃｉｅｔｅ Ｃｈｉｍｉｑｕｅ ｄｅ Ｆｒａｎｃｅ, １９６８， （１０）， ｐ．４２１０−４２２１
JPN6010040349, Ｋ． Ｓａｏｔｏｍｅ ｅｔ ａｌ．, "Ｔｈｅ ｓｙｎｔｈｅｓｉｓ ｏｆ ｄｉｃａｒｂｏｘｙｌｉｃ ａｃｉｄｓ ｃｏｎｔａｉｎｉｎｇ ｏｘａｄｉａｚｏｌｅ ｒｉｎｇｓ ａｎｄ ｐｏｌｙａｍｉｄｅｓ ｄｅｒｉｖｅｄ ｆｒｏｍ ｔｈｅｍ", Ｍａｋｒｏｍｏｌｅｋｕｌａｒｅ Ｃｈｅｍｉｅ, １９６７， １００， ｐ．９１−９９
Attorney, Agent or Firm:
Masatake Shiga (7 outside)