Title:
【発明の名称】麻酔活性を有する、3α-ヒドロキシ-3βメトキシメチル-21-複素環式置換ステロイド
Document Type and Number:
Japanese Patent JP2002543218
Kind Code:
A
Abstract:
This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein: R1 is H or methyl; R2 is 5alpha- or 5beta-H; R3 is an optionally substituted N-attached heteroaryl group or a group -X-R4; R4 is an optionally substituted carbon-attached heteroaryl group; and X is O, S or N. The invention also is directed to the use of 3alpha-hydroxy-3beta-methoxymethyl-substituted steroids as sedative/hypnotics and for inducing anesthesia.
Inventors:
Hogenkamp, Dark Jay.
Application Number:
JP2000615643A
Publication Date:
December 17, 2002
Filing Date:
April 28, 2000
Export Citation:
Assignee:
Purdue Pharma Limited
International Classes:
A61K31/58; A61P23/00; A61P25/20; C07J31/00; A61K31/573; C07J33/00; C07J43/00; (IPC1-7): C07J43/00; A61K31/573; A61P23/00; A61P25/20
Attorney, Agent or Firm:
Shusaku Yamamoto