Title:
【発明の名称】DNA構築物
Document Type and Number:
Japanese Patent JP2003504033
Kind Code:
A
Abstract:
The present invention provides novel DNA constructs comprising a transcriptional regulatory sequence comprising a polynucleotide derivable from the eIF4A1 gene promoter. In preferred embodiments, the polynucleotide further comprises a polynucleotide derivable from the eIF4A gene introns, particularly intron 1. Host cells harbouring the constructs are also provided. These novel constructs have applications in gene therapy, DNA vaccines and in the commercial production of proteins.
Inventors:
David, Robert, Greaves
Lindy, Thomsen
Ian, Richard, Catch pole
Martin, James, Ford
Lindy, Thomsen
Ian, Richard, Catch pole
Martin, James, Ford
Application Number:
JP2001508366A
Publication Date:
February 04, 2003
Filing Date:
July 05, 2000
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
C12N15/09; A61K35/76; A61K38/00; A61K39/395; A61K48/00; A61P35/00; A61P43/00; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12N15/85; C12P21/00; A61K39/00; (IPC1-7): C12N15/09; A61K35/76; A61K38/00; A61K39/395; A61K48/00; A61P35/00; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/00
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Attorney, Agent or Firm:
Kenji Yoshitake (3 others)