Title:
【発明の名称】メラノコルチン-4受容体ゴニストとしての置換ピペリジン
Document Type and Number:
Japanese Patent JP2003505435
Kind Code:
A
Abstract:
Certain novel substituted piperidine compounds are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction. Also provided are methods of treating sexual dysfunction with a compound that is a selective agonist of MC-4R over any other human melanocortin receptor.
Inventors:
Bakshi, Rahman Kay
Barakatto, Khalid Jei
Naviganda, Rabbi Pee
Paltsuki, Brenda El
Pachiet, Arthur A.
Severt, ear sue
Yes
Juan del Proof, Leonardus Her Te
Barakatto, Khalid Jei
Naviganda, Rabbi Pee
Paltsuki, Brenda El
Pachiet, Arthur A.
Severt, ear sue
Yes
Juan del Proof, Leonardus Her Te
Application Number:
JP2001512328A
Publication Date:
February 12, 2003
Filing Date:
May 31, 2000
Export Citation:
Assignee:
Merck End-Campany Inc.
International Classes:
A61K31/404; A61K31/454; A61K31/4725; A61K31/4985; A61P3/04; A61P3/10; A61P15/00; A61P15/10; C07D401/12; C07D401/14; C07D405/14; C07D413/14; C07D417/14; C07D471/04; C07D521/00; (IPC1-7): C07D401/12; A61K31/404; A61K31/454; A61K31/4725; A61K31/4985; A61P3/04; A61P3/10; A61P15/00; A61P15/10; C07D401/14; C07D405/14; C07D471/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (5 outside)