Title:
【発明の名称】H-TYR-D-ALA-PHE(F)-PHE-NH2の製造方法
Document Type and Number:
Japanese Patent JP2003509437
Kind Code:
A
Abstract:
The present invention discloses a new and improved process for the preparation of the tetrapeptide H-Tyr-D-Ala-Phe(F)-Phe-NH2 that is a peptide of formula (I), or a pharmaceutically acceptable salt thereof, as well as new intermediates in the preparation thereof. The novel process is a fragment synthesis and suitable for large-scale production.
Inventors:
Morten Elburg
Henry Franssen
Martos Nilsson
Henry Franssen
Martos Nilsson
Application Number:
JP2001523626A
Publication Date:
March 11, 2003
Filing Date:
September 07, 2000
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K38/00; A61P29/02; A61P43/00; C07K1/02; C07K1/06; C07K5/10; C07K5/107; (IPC1-7): C07K5/107; C07K1/02; C07K1/06
Attorney, Agent or Firm:
Chika Takagi (2 outside)