Title:
【発明の名称】原核生物の核酸結合蛋白質による分子性物質の導入方法
Document Type and Number:
Japanese Patent JP2003513634
Kind Code:
A
Abstract:
The invention relates to a method for the transfer of molecular substances, for example proteins or nucleic acids in cells, in the case of using DNA combined with a possible gene expression. A prokaryotic nucleic acid-binding protein is used for the transfer, which is preferably obtained from a thermostable organism. Where the substance to be transferred is a nucleic acid, the protein forms a reversible complex with the nucleic acid. The prokaryotic protein condenses and compacts the nucleic acids. Said nucleic acids can be taken up in the target cells after suitable incubation.
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Inventors:
Behm, Geralt
Esser, Dirk
Esser, Dirk
Application Number:
JP2001535582A
Publication Date:
April 15, 2003
Filing Date:
November 03, 2000
Export Citation:
Assignee:
ATGAE Progenomics Akchen Gesell Shaft
International Classes:
A61K31/711; A61K31/715; A61K38/00; A61K38/22; A61K38/43; A61K48/00; A61P7/00; A61P21/04; A61P31/18; A61P35/00; A61P43/00; C07K14/005; C07K19/00; C12N15/09; C12N5/10; C12N15/87; (IPC1-7): C12N15/09; A61K31/711; A61K31/715; A61K38/00; A61K38/22; A61K38/43; A61K48/00; A61P7/00; A61P21/04; A61P31/18; A61P35/00; A61P43/00; C12N5/10
Attorney, Agent or Firm:
Hironobu Onda (1 person outside)