Title:
【発明の名称】プロテインC誘導体
Document Type and Number:
Japanese Patent JP2003514545
Kind Code:
A
Abstract:
Novel human protein C derivatives are described. These derivatives have increased anti-coagulation activity compared to wild-type protein C and retain the biological activity of the wild-type human protein C. These derivatives will require either less frequent administration and/or smaller dosage than wild-type human protein C in the treatment of acute coronary syndromes, vascular occlusive disorders, hypercoagulable states, thrombotic disorders and disease states predisposing to thrombosis.
Inventors:
Bruce Edward Garritz
Brian William Grinnell
Juan Lihua
Brian edward jones
Brian William Grinnell
Juan Lihua
Brian edward jones
Application Number:
JP2001538951A
Publication Date:
April 22, 2003
Filing Date:
November 06, 2000
Export Citation:
Assignee:
ELI LILLY AND COMPANY
International Classes:
B65D23/00; A61K38/48; A61K45/00; A61P7/00; A61P7/02; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P17/02; A61P31/04; A61P31/12; A61P41/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/50; C12N9/64; C12N15/09; A61K38/00; (IPC1-7): C12N15/09; A61K38/48; A61K45/00; A61P7/00; A61P7/02; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P17/02; A61P31/04; A61P31/12; A61P41/00; B65D23/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/50
Attorney, Agent or Firm:
Kaoru Aoyama (3 people outside)