Title:
【発明の名称】腫瘍細胞において発現し、かつ免疫応答の調節に関与する遺伝子のクローニング、発現及び特徴付け
Document Type and Number:
Japanese Patent JP2003516126
Kind Code:
A
Abstract:
The invention concerns the identification and the characterisation of a novel gene expressed in tumour cells and involved in the regulation of the immune response, the cloning and the characterisation of its cDNA and the corresponding polypeptides. The invention also concerns vectors containing a nucleic acid coding for said gene, cells transformed by said vectors and diagnostic methods and selection methods of a chemical or biological compound capable of directly or indirectly interacting with a nucleic acid or a polypeptide of the invention. The invention further concerns compounds for treating immune pathologies, in particular autoimmune diseases and cancer.
Inventors:
Del Nestou, Eve
Magistrelli, Giovanni
Genin, Pascal
Bonne Foy, Jean-Eve
Magistrelli, Giovanni
Genin, Pascal
Bonne Foy, Jean-Eve
Application Number:
JP2001533984A
Publication Date:
May 13, 2003
Filing Date:
October 30, 2000
Export Citation:
Assignee:
Pierre Fabre Medicaman
International Classes:
G01N33/50; A61K31/7088; A61K35/76; A61K38/00; A61K39/395; A61K48/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P37/00; A61P37/02; C07K14/47; C07K14/705; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12Q1/68; G01N33/15; G01N33/53; (IPC1-7): C12N15/09; A61K31/7088; A61K35/76; A61K38/00; A61K39/395; A61K48/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/02; C07K14/47; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53
Attorney, Agent or Firm:
Takashima Hajime