Title:
【発明の名称】親水性ソマトスタチン類似体
Document Type and Number:
Japanese Patent JP2003517999
Kind Code:
A
Abstract:
The invention features novel somatostatin analogs that may be readily labeled with toxic or non-toxic detectable labels. These unlabeled and labeled analogs are useful for specifically targeting somatostatin receptor bearing cells, in particular neoplastic cells. Labeled analogs are useful, for example, for tumor localization and detection. Where labeled with a toxic label (e.g., radioactivity), the analogs are useful for the targeted delivery of toxicity to somatostatin receptor-bearing cells, in particular neoplastic cells.Also disclosed are methods for treating and detecting neoplasms, and methods for imaging somatostatin receptor-bearing cells.
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Inventors:
Koy David H.
Murphy William A.
Waltering Eugene A.
Phacelia Joseph A.
Drawant george
Murphy William A.
Waltering Eugene A.
Phacelia Joseph A.
Drawant george
Application Number:
JP2000583949A
Publication Date:
June 03, 2003
Filing Date:
October 20, 1999
Export Citation:
Assignee:
Turain University
International Classes:
A61K51/00; A61K51/08; G01N33/48; C07K14/655; A61K38/00; (IPC1-7): C07K14/655; G01N33/48
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)