Title:
【発明の名称】ヒトcAMP依存性プロテインキナーゼの触媒サブユニットの新規なスプライス変異体の同定とそれらの使用
Document Type and Number:
Japanese Patent JP2003518385
Kind Code:
A
Abstract:
The Cbeta gene encodes at least 6 different gene products, designated Cbeta1, Cbeta2, Cbeta3, Cbeta4, Cbeta4ab and Cbeta4abc. As is the case with the murine and bovine splice variants, all the human Cbeta splice variants vary in the N-terminal part preceding the part encoded by exon 2. Homologues to all Cbeta splice variants identified in mouse and bovine were identified in human (Cbeta1, Cbeta2, Cbeta3 and Cbeta4) in addition to two novel Cbeta splice variants (Cbeta4ab and Cbeta4abc), that have previously not been identified in any other species. Genomic DNA- and cDNA sequences encode splice variants and include the nucleotide sequences shown in SEQ ID NO: 1, 2, 3, 4, 5 and 6 respectively. The proteins are new splice variants of the Cbeta protein.
Inventors:
Orstavik, Sigurd
Rainton, Nils
Frengen, Erik
Langeland, Bjorn, Torre
Janssen, Torre
Skullheg, Bjorn, S.
Rainton, Nils
Frengen, Erik
Langeland, Bjorn, Torre
Janssen, Torre
Skullheg, Bjorn, S.
Application Number:
JP2001548684A
Publication Date:
June 10, 2003
Filing Date:
December 22, 2000
Export Citation:
Assignee:
Orstavik, Sigurd
Rainton, Nils
Frengen, Erik
Langeland, Bjorn, Torre
Janssen, Torre
Skullheg, Bjorn, S.
Rainton, Nils
Frengen, Erik
Langeland, Bjorn, Torre
Janssen, Torre
Skullheg, Bjorn, S.
International Classes:
G01N33/48; A61K31/7088; A61K38/45; A61K45/00; A61K48/00; A61P37/04; A61P43/00; C12N9/00; C12N9/12; C12N9/99; C12N15/09; C12Q1/02; C12Q1/48; C12Q1/68; G01N21/78; G01N33/15; G01N33/50; G01N33/53; G01N33/569; A61K38/00; (IPC1-7): C12N15/09; A61K31/7088; A61K38/45; A61K45/00; A61K48/00; A61P37/04; A61P43/00; C12N9/00; C12N9/12; C12N9/99; C12Q1/02; C12Q1/48; C12Q1/68; G01N21/78; G01N33/15; G01N33/48; G01N33/50; G01N33/53
Attorney, Agent or Firm:
Akira Asamura (3 outside)