Title:
【発明の名称】虚血の治療方法
Document Type and Number:
Japanese Patent JP2003522727
Kind Code:
A
Abstract:
A method for treating ischemia by administering deltorphins to a mammal. Deltorphin I SEQ ID NO:1, deltorphin II SEQ ID NO:2 or combinations of deltorphins I SEQ ID NO:1 and II SEQ ID NO:2 may be administered. A deltorphin concentration of about 0.5-20 mg/kg, or alternatively 1-1000 mu g/kg body weight of the mammal in a physiologically acceptable formulation is administered up to four hours after an ischemic episode. Deltorphins may also be administered prior to or concurrently with onset of ischemia. Cerebral or spinal cord ischemia or ischemic heart disease may be treated using the method of the invention.
Inventors:
Oertigen, Peter, Earl
Kindy, Mark, S
Bishop, Paul, Dee
Kindy, Mark, S
Bishop, Paul, Dee
Application Number:
JP2000546790A
Publication Date:
July 29, 2003
Filing Date:
April 30, 1999
Export Citation:
Assignee:
University of Kentucky Research Foundation
International Classes:
A61K9/10; A61K38/00; A61K38/08; A61P9/00; A61P9/10; A61P43/00; A61K9/08; C07K7/06; (IPC1-7): A61K38/00; A61K9/08; A61K9/10; A61P9/00; A61P9/10; A61P43/00
Attorney, Agent or Firm:
Akira Asamura (3 outside)