Title:
【発明の名称】細胞保護性ステロイド(II)
Document Type and Number:
Japanese Patent JP2003522794
Kind Code:
A
Abstract:
A method is provided for treating a patient in need of therapy for acute neuronal degeneration due to metabolic compromise of central or peripheral nervous system cells comprising administering to that patient a therapeutically effective amount of a 7alpha-hydroxy substituted steroid selected from 7alpha-hydroxy-derivatives of estradiols, dehydroepiandrosterones and pregnenolones, and metabolic precursors thereof. Use of such compounds for manufacture of medicaments and neuroprotective compositions are also provided.
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Inventors:
Latte, Richard Frank
Sekul, Jonathan Robert
Martin Frank, Frank
Wurfeld, Ernest Ahn
Sekul, Jonathan Robert
Martin Frank, Frank
Wurfeld, Ernest Ahn
Application Number:
JP2001559471A
Publication Date:
July 29, 2003
Filing Date:
February 15, 2001
Export Citation:
Assignee:
HUNTER-FLEMING LIMITED
University of Edinburgh
BTG International Limited
University of Edinburgh
BTG International Limited
International Classes:
A61K31/565; A61K31/567; A61K31/5685; A61K31/57; A61P9/10; A61P25/00; A61P25/02; A61P25/28; A61P43/00; C07J1/00; (IPC1-7): A61K31/565; A61K31/5685; A61K31/57; A61P25/00; A61P25/02; A61P43/00
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)