Title:
【発明の名称】疼痛の治療のためのヒドロキシフェニルピペリジン-4-イリデン-メチルベンズアミド誘導体
Document Type and Number:
Japanese Patent JP2003529596
Kind Code:
A
Abstract:
Compounds of general formula I R<1 >is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, triazolyl and thiazolyl; where each R<1 >phenyl ring and R<1 >heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain.
Inventors:
William brown
Christopher Walpole
Zonyoung Way
Christopher Walpole
Zonyoung Way
Application Number:
JP2001572494A
Publication Date:
October 07, 2003
Filing Date:
March 30, 2001
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K31/4465; A61K31/4523; A61K31/4525; A61K31/4535; A61K31/4545; A61P1/00; A61P25/00; A61P25/02; A61P25/04; C07D211/68; C07D211/70; C07D405/06; C07D401/06; C07D409/06; C07D417/06; (IPC1-7): C07D211/70; A61K31/4465; A61K31/4525; A61K31/4535; A61K31/4545; A61P1/00; A61P25/02; A61P25/04; C07D401/06; C07D405/06; C07D409/06; C07D417/06
Foreign References:
| WO1997023466A1 | 1997-07-03 | |||
| WO1999001033A1 | 1999-01-14 | |||
| WO1999033806A1 | 1999-07-08 | |||
| WO1998028275A1 | 1998-07-02 |
Attorney, Agent or Firm:
Chika Takagi (2 outside)