Title:
【発明の名称】キナゾリン化合物
Document Type and Number:
Japanese Patent JP2003530387
Kind Code:
A
Abstract:
The invention concerns quinazoline derivatives of Formula (I) wherein ring A is phenyl or a 5-or 6-membered heterocyclic ring which may be saturated, partially saturated or unsaturated and may be aromatic or non-aromatic and which contains 1, 2 or 3 ring heteroatoms selected from O, N and S; Z is -O-, -NH- or -S-; and X1, R1, R2, R3, m and R4 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in producing an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals, and in the treatment of disease states such as cancer, rheumatoid arthritis and psorlasis.
Inventors:
Enekin, Lauren Francois Andre
Stowex, Elaine Sophie Elizabeth
Stowex, Elaine Sophie Elizabeth
Application Number:
JP2001575560A
Publication Date:
October 14, 2003
Filing Date:
April 03, 2001
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
A61K31/505; A61K31/517; A61P3/10; A61P9/00; A61P9/10; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P37/06; A61P41/00; A61P43/00; C07D239/94; C07D401/12; C07D403/12; C07D417/12; (IPC1-7): C07D239/94; A61K31/517; A61P3/10; A61P9/00; A61P9/10; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P37/06; A61P41/00; A61P43/00; C07D401/12; C07D403/12; C07D417/12
Domestic Patent References:
| JPH0673025A | 1994-03-15 |
Foreign References:
| WO1998013354A1 | 1998-04-02 | |||
| WO1997030035A1 | 1997-08-21 |
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)