Title:
【発明の名称】マトリックスメタロプロテイナーゼの阻害剤としてのスルホンアミド誘導体
Document Type and Number:
Japanese Patent JP2003530389
Kind Code:
A
Abstract:
The present invention provides a novel sulfonamide derivative of general formula (I) useful as an inhibitor of matrix metalloproteinase (MMP), its isomers, pharmaceutically acceptable salts thereof and a process for preparing the same. Since the sulfonamide derivatives of the present invention selectively inhibit MMP activity in vitro, the MMP inhibitors comprising the sulfonamide derivatives as an effective ingredient can be practically applied for the prevention and treatment of all sorts of diseases caused by overexpression and overactivation of MMP.
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Inventors:
Park, Yong-Jun
Fly, fly-yan
Yeo, Ji-Wook
Chae, Myeong-Yoon
Park, Sun-Hyun
Min, Haiye Kyun
Hyun-Gyu Park
Ryu, Jeong Ho
Kim, Kyun-Tul
Lee, John-Wook
Fly, fly-yan
Yeo, Ji-Wook
Chae, Myeong-Yoon
Park, Sun-Hyun
Min, Haiye Kyun
Hyun-Gyu Park
Ryu, Jeong Ho
Kim, Kyun-Tul
Lee, John-Wook
Application Number:
JP2001575566A
Publication Date:
October 14, 2003
Filing Date:
April 07, 2001
Export Citation:
Assignee:
Samsung Electronics Company Limited
International Classes:
A61K31/423; A61K31/428; A61K31/4439; A61K31/4523; A61K31/4725; A61K31/5377; A61K31/541; A61K31/662; A61P1/02; A61P9/10; A61P11/00; A61P13/12; A61P19/00; A61P19/02; A61P19/10; A61P27/02; A61P29/00; A61P35/00; A61P37/00; C07D263/58; C07D277/74; C07D413/12; C07D417/12; C07F9/6541; (IPC1-7): C07D263/58; A61K31/423; A61K31/428; A61K31/4439; A61K31/4523; A61K31/4725; A61K31/5377; A61K31/541; A61K31/662; A61P1/02; A61P9/10; A61P11/00; A61P13/12; A61P19/00; A61P19/02; A61P19/10; A61P27/02; A61P29/00; A61P35/00; A61P37/00; C07D277/74; C07D413/12; C07D417/12; C07F9/6541
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)