Title:
【発明の名称】シクロプロピル縮合ピロリジン骨格を有するジペプチジルペプチダーゼIVの阻害剤及び方法
Document Type and Number:
Japanese Patent JP2003531118
Kind Code:
A
Abstract:
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided. The provided compounds can be used for treating diabetes and related diseases, especially Type II diabetes, and other diseases as set out herein, employing such DP 4 inhibitor or a combination of such DP 4 inhibitor and one or more of another antidiabetic agent such as metformin, glyburide, troglitazone, pioglitazone, rosiglitazone and/or insulin and/or one or more of a hypolipidemic agent and/or anti-obesity agent and/or other therapeutic agent.
Inventors:
Jeffrey A. Roble
Richard B. Sarsky
David Jay Augeri
David Earl Magnin
Lawrence G. Haman
David A. Vitevener
Richard B. Sarsky
David Jay Augeri
David Earl Magnin
Lawrence G. Haman
David A. Vitevener
Application Number:
JP2001567699A
Publication Date:
October 21, 2003
Filing Date:
March 05, 2001
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D401/06; A61K31/403; A61K31/4045; A61K31/454; A61K45/00; A61P1/00; A61P1/04; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P9/10; A61P15/00; A61P19/02; A61P19/10; A61P25/18; A61P31/18; A61P37/02; A61P37/06; A61P43/00; C07C271/12; C07D209/52; C07D403/06; (IPC1-7): C07D209/52; A61K31/403; A61K31/4045; A61K31/454; A61K45/00; A61P1/00; A61P1/04; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P9/10; A61P15/00; A61P19/02; A61P19/10; A61P25/18; A61P31/18; A61P37/02; A61P37/06; A61P43/00; C07D401/06; C07D403/06
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)
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