Title:
【発明の名称】ナフトキノン誘導体および結核の治療および制御におけるその使用
Document Type and Number:
Japanese Patent JP2003531813
Kind Code:
A
Abstract:
Naphthoquinone derivatives of Formula (1): wherein, R represents an OH group, methyl ether, ethyl ether or a similar ether; R1 represents a methyl, ethyl or similar aliphatic hydrocarbon derivative; R2 and R3 each independently represent hydrogen or a group selected from: (A), (B), or (C) wherein R5 represents an OH group, methyl ether, ethyl ether or a similar ether and R6 represents a methyl, ethyl or similar aliphatic hydrocarbon derivative; R4 represents hydrogen or a group selected from: (D), (E) or (F) wherein R7 represents an OH group, methyl ether, ethyl ether or a similar ether and R8 represents a methyl, ethyl or similar aliphatic hydrocarbon derivative; or pharmaceutically acceptable salts thereof, are useful for the treatment and/or control of a tuberculosis in a patient caused by Mycobacterium tuberculosis.
Inventors:
Mayer, Jacobs Johannes Marion
Ral, Namrita
Ral, Namrita
Application Number:
JP2001506968A
Publication Date:
October 28, 2003
Filing Date:
June 22, 2000
Export Citation:
Assignee:
University of Pretoria
South Africa Medical Research Council
South Africa Medical Research Council
International Classes:
A61P31/06; A61K31/122; C07C50/32; (IPC1-7): C07C50/32; A61K31/122; A61P31/06
Attorney, Agent or Firm:
Ippei Watanabe