Title:
【発明の名称】インテグリン阻害剤としての1-(アミノフェニル)-2-ピロリドン類
Document Type and Number:
Japanese Patent JP2003535036
Kind Code:
A
Abstract:
The invention comprises novel compounds that are effective in the prophylaxis and treatment of diseases, such as integrin receptors mediated diseases, in particular, diseases or conditions mediated by integrin receptors, such as a alphavbeta3, alphavbeta5, alphavbeta6, alpha5beta1 and the like. The invention encompasses novel compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of such diseases and disorders. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Inventors:
Dominguez, Ceria
Qian, Qing
Shii, Nin
Shiu, Simin
Han, Nian Ho
Li Yu, Ching Yan
Hoang Chi
Sigmund, Aaron
Handley, Michael
Liu, Lombin
Kseljov, Alexander S.
Qian, Qing
Shii, Nin
Shiu, Simin
Han, Nian Ho
Li Yu, Ching Yan
Hoang Chi
Sigmund, Aaron
Handley, Michael
Liu, Lombin
Kseljov, Alexander S.
Application Number:
JP2001544720A
Publication Date:
November 25, 2003
Filing Date:
December 11, 2000
Export Citation:
Assignee:
Amjien Incorporated
International Classes:
C07D401/06; A61K31/402; A61K31/4025; A61K31/4178; A61K31/4355; A61K31/438; A61K31/4406; A61K31/4709; A61K31/496; A61K31/506; A61P3/10; A61P9/00; A61P9/10; A61P17/02; A61P19/00; A61P27/02; A61P29/00; A61P35/00; A61P35/04; C07D207/277; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/14; C07D417/14; C07D471/10; C07D207/26; (IPC1-7): C07D207/277; A61K31/402; A61K31/4025; A61K31/4178; A61K31/4355; A61K31/438; A61K31/4406; A61K31/4709; A61K31/496; A61K31/506; A61P3/10; A61P9/00; A61P9/10; A61P17/02; A61P19/00; A61P27/02; A61P29/00; A61P35/00; A61P35/04; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/14; C07D417/14; C07D471/10
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)