Title:
【発明の名称】抗菌剤の経口吸収を改善するための組成物および方法
Document Type and Number:
Japanese Patent JP2003535911
Kind Code:
A
Abstract:
The present invention provides compositions and methods for increasing absorption of antibacterial agents, particularly third generation cephalosporin antibacterial agents, in oral dosage solid and/or suspension forms. Specifically, the composition is comprised of a biopolymer that is preferably swellable and/or mucoadhesive, an antimicrobial agent, and a cationic binding agent contained within the biopolymer such that the binding agent is ionically bound or complexed to at least one member selected from the group consisting of the biopolymer and the antimicrobial agent.
Inventors:
Choi, Soun-ho
Lee, Jung-Sue
Keith, Dennis
Lee, Jung-Sue
Keith, Dennis
Application Number:
JP2002503335A
Publication Date:
December 02, 2003
Filing Date:
June 18, 2001
Export Citation:
Assignee:
Cubist Pharmaceuticals, Inc.
International Health Management Associates, Inc.
University of Utah Research Foundation
International Health Management Associates, Inc.
University of Utah Research Foundation
International Classes:
A61K9/16; A61K9/22; A61K9/52; A61K31/546; A61K38/00; A61K38/12; A61K38/14; A61K47/12; A61K47/14; A61K47/48; A61P31/04; (IPC1-7): A61K47/48; A61K9/22; A61K9/52; A61K31/546; A61K38/00; A61K47/12; A61K47/14; A61P31/04
Domestic Patent References:
| JPH0790002A | 1995-04-04 | |||
| JPH1192402A | 1999-04-06 |
Foreign References:
| EP0526862A1 | 1993-02-10 | |||
| WO1999049868A1 | 1999-10-07 |
Attorney, Agent or Firm:
Seiji Yanagida (1 person outside)