Title:
腫瘍性細胞成長阻害のための組成物及び方法
Document Type and Number:
Japanese Patent JP2004500071
Kind Code:
A
Abstract:
The present invention concerns methods and compositions for inhibiting neoplastic cell growth. In particular, the present invention concerns antitumor compositions and methods for the treatment of tumors. The invention further concerns screening methods for identifying growth inhibitory, e.g., antitumor compounds. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Inventors:
Ashkenazi, Avi, J.
Goddard, Audrey
Gurney, Austin, Elle.
Napiere, Mary, A.
Watanabe, Colin, Kay.
Wood, William, Eye.
Goddard, Audrey
Gurney, Austin, Elle.
Napiere, Mary, A.
Watanabe, Colin, Kay.
Wood, William, Eye.
Application Number:
JP2001550255A
Publication Date:
January 08, 2004
Filing Date:
November 08, 2000
Export Citation:
Assignee:
GENENTECH,INC.
International Classes:
C12N15/09; A61K38/00; A61K38/18; A61K39/00; A61K39/395; A61K45/00; A61K45/06; A61P1/00; A61P11/00; A61P13/10; A61P13/12; A61P15/00; A61P25/00; A61P35/00; A61P35/02; C07K14/00; C07K14/47; C07K14/71; C07K16/18; C07K16/28; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12N15/62; C12P21/02; C12P21/08; (IPC1-7): C12N15/09; A61K38/00; A61K39/00; A61K45/00; A61K45/06; A61P1/00; A61P11/00; A61P13/10; A61P13/12; A61P15/00; A61P25/00; A61P35/00; A61P35/02; C07K14/47; C07K16/18; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori