Title:
パーキンソン病の処置のための組成物および方法
Document Type and Number:
Japanese Patent JP2004500331
Kind Code:
A
Abstract:
This invention provides compositions and methods for increasing cellular respiration of melanized catecholamine neurons, and methods for alleviating symptoms or stopping appearance and/or progression of symptoms of Parkinson's Disease, and methods for preventing symptoms of on-off syndrome associated with treatment with dopamine or a dopamine agonist of a patient suffering symptoms of a disease selected from the group consisting of idiopathic and atypical Parkinson's disease, conditions characterized by nigrostriatal degeneration and multiple system atrophy, said methods comprising administering to said patient an effective amount of a neuromelanin-binding composition having a quinoline ring in a suitable pharmaceutical carrier. Preferably the composition comprises (-)-chloroquine.
Inventors:
Nelson, Jody
Application Number:
JP2001508933A
Publication Date:
January 08, 2004
Filing Date:
July 13, 2000
Export Citation:
Assignee:
Alpha Research Group, LRC
International Classes:
A61K31/355; A61K31/375; A61K31/47; A61K31/4706; A61K47/48; A61P25/16; (IPC1-7): A61K31/4706; A61P25/16
Foreign References:
| US5430039A | 1995-07-04 |
Attorney, Agent or Firm:
Hidesaku Yamamoto