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Title:
治療剤及び診断剤としての新規ポリアミン類似体
Document Type and Number:
Japanese Patent JP2004509845
Kind Code:
A
Abstract:
Novel "bispolyamine" inhibitor compounds of polyamine transport are disclosed. These compounds are useful pharmaceutical agents for treating diseases where it is desired to inhibit polyamine transport or other polyamine binding proteins, for example cancer and post-angioplasty injury. These compounds display desirable activities both for diagnostic and research assays and therapy.

Inventors:
Nicholas M. J. Vermuulin
Christine El O'Day
Heather Kay Web
Mark Earl Burns
Donald E. Bergstrom
Application Number:
JP2002500833A
Publication Date:
April 02, 2004
Filing Date:
May 31, 2001
Export Citation:
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Assignee:
Mediquest Therapeutics Inc.
International Classes:
C07D233/90; A61K31/16; A61K31/165; A61K31/166; A61K31/17; A61K31/18; A61K31/185; A61K31/197; A61K31/198; A61K31/27; A61K31/277; A61K31/341; A61K31/381; A61K31/401; A61K31/405; A61K31/415; A61K31/42; A61K31/427; A61K31/433; A61K31/44; A61K31/4436; A61K31/47; A61K31/473; A61K31/506; A61K47/48; A61P1/12; A61P9/10; A61P9/12; A61P17/06; A61P19/10; A61P25/00; A61P25/08; A61P25/18; A61P25/24; A61P25/28; A61P31/04; A61P31/12; A61P33/00; A61P35/00; A61P37/02; A61P43/00; C07C211/13; C07C211/52; C07C211/54; C07C233/36; C07C233/39; C07C233/40; C07C233/62; C07C233/63; C07C233/78; C07C235/20; C07C235/34; C07C235/50; C07C235/74; C07C237/10; C07C237/20; C07C237/22; C07C237/42; C07C239/16; C07C271/20; C07C271/22; C07C275/28; C07C275/40; C07C279/14; C07C311/05; C07C311/06; C07C311/10; C07C311/14; C07C311/18; C07C311/19; C07C311/24; C07C311/29; C07C311/41; C07C311/42; C07C311/44; C07C323/60; C07C327/42; C07D207/16; C07D209/20; C07D209/22; C07D213/81; C07D213/82; C07D215/36; C07D215/52; C07D219/04; C07D231/14; C07D233/84; C07D261/18; C07D285/14; C07D285/22; C07D307/68; C07D307/91; C07D333/24; C07D333/34; C07D333/38; C07D401/04; C07D409/04; C07D409/12; C07D417/04; C07F9/645; G01N33/53; (IPC1-7): C07C233/36; A61K31/16; A61K31/165; A61K31/166; A61K31/17; A61K31/18; A61K31/185; A61K31/197; A61K31/198; A61K31/27; A61K31/277; A61K31/341; A61K31/381; A61K31/401; A61K31/405; A61K31/415; A61K31/42; A61K31/427; A61K31/433; A61K31/44; A61K31/4436; A61K31/47; A61K31/473; A61K31/506; A61P1/12; A61P9/10; A61P9/12; A61P17/06; A61P19/10; A61P25/00; A61P25/08; A61P25/18; A61P25/24; A61P25/28; A61P31/04; A61P31/12; A61P33/00; A61P35/00; A61P37/02; A61P43/00; C07C233/40; C07C233/63; C07C233/78; C07C235/50; C07C237/10; C07C271/22; C07C275/40; C07C311/05; C07C311/14; C07C311/18; C07C311/29; C07C311/44; C07C323/60; C07D207/16; C07D209/20; C07D213/82; C07D215/36; C07D215/52; C07D219/04; C07D233/90; C07D261/18; C07D285/14; C07D307/68; C07D333/24; C07D333/34; C07D333/38; C07D409/04; C07D409/12; C07D417/04
Foreign References:
WO1999003823A21999-01-28
WO1999054283A11999-10-28
Attorney, Agent or Firm:
Yasuo Yasutomi