Title:
フラビウイルスおよびペスチウイルス治療のための方法および組成物
Document Type and Number:
Japanese Patent JP2004510698
Kind Code:
A
Abstract:
The present invention provides pharmaceutical compositions for the treatment of a flavivirus or pestivirus infection in a host, wherein the infection is not hepatitis C, comprising an antivirally effective amount of a 2'-C-branched nucleoside or a 2'-C-branched ribofuranosyl nucleoside or pharmaceutically acceptable salts or esters thereof, in combination with one or more other anti-flavivirus or pestivirus agent. The present invention further provides for the use of a 2'-C-branched nucleoside or a 2'-C-branched ribofuranosyl nucleoside or pharmaceutically acceptable salts or esters thereof, in the manufacture of a medicament for the treatment of a flavivirus or pestivirus infection in a host, wherein the infection is not hepatitis C.
Inventors:
Somadosi, Jiyan-Pierre
Rakotura, Paolo
Rakotura, Paolo
Application Number:
JP2002500895A
Publication Date:
April 08, 2004
Filing Date:
May 23, 2001
Export Citation:
Assignee:
Idenix (Cayman) Limited
Unibercita Detsuri Stoday Day Cagliari
Unibercita Detsuri Stoday Day Cagliari
International Classes:
A61K31/7064; A61K31/7068; A61K31/7072; A61K31/7076; A61K31/708; A61P1/04; A61P1/12; A61P25/00; A61P31/12; A61P31/14; A61P31/18; A61P43/00; C07H19/06; C07H19/067; C07H19/10; C07H19/16; C07H19/167; C07H19/20; A61K; A61P; C07H; (IPC1-7): C07H19/067; A61K31/7064; A61K31/7068; A61K31/7072; A61K31/7076; A61K31/708; A61P1/04; A61P1/12; A61P25/00; A61P31/12; A61P31/14; A61P31/18; A61P43/00; C07H19/10; C07H19/167; C07H19/20
Domestic Patent References:
| JPH01283285A | 1989-11-14 |
Foreign References:
| WO1998016184A2 | 1998-04-23 |
Other References:
NUCLEOSIDES & NUCLEOTIDES, vol. Vol.16, No.7-9, JPN7011003259, 1997, pages 1457 - 1460, ISSN: 0002011620
J. MED. CHEM., vol. 12, JPN6011047247, 1969, pages 306 - 309, ISSN: 0002011621
SYNTHESIS, JPN6011047248, 1992, pages 773 - 778, ISSN: 0002011622
ANTIVIRAL RESEARCH, vol. 7, JPN6011047250, 1987, pages 151 - 160, ISSN: 0002011623
VIROLOGY, vol. 187, JPN6011047251, 1992, pages 73 - 83, ISSN: 0002011624
J. MED. CHEM., vol. 12, JPN6011047247, 1969, pages 306 - 309, ISSN: 0002011621
SYNTHESIS, JPN6011047248, 1992, pages 773 - 778, ISSN: 0002011622
ANTIVIRAL RESEARCH, vol. 7, JPN6011047250, 1987, pages 151 - 160, ISSN: 0002011623
VIROLOGY, vol. 187, JPN6011047251, 1992, pages 73 - 83, ISSN: 0002011624
Attorney, Agent or Firm:
Yoshio Kawaguchi
Mitsuru Inoue
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuru Inoue
Akio Ichiiri
Makoto Ono
Katsuma Osaki