Title:
IV型ヒトアデニル酸シクラーゼの調節
Document Type and Number:
Japanese Patent JP2004511245
Kind Code:
A
Abstract:
An adenylate cyclase type IV protein, cDNA, and reagents which regulate human adenylate cyclase type IV can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, diseases that are caused by aberrant activity of this enzyme and diseases whose symptoms can be ameliorated by stimulating or inhibiting the activity of type IV adenylyl cyclase. Such diseases include, for example, hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; restenosis; atherosclerosis; diseases characterized by excessive smooth muscle cells or reduced smooth muscle cell proliferation; aneurysms; wound healing; stroke; ischemia; ulcers; asthma; allergies; benign prostatic hypertrophy; migraine; vomiting; psychotic; and neurological disorders, including anxiety, schizophrenia, manic depression, depression, delirium, dementia, and severe mental retardation, degenerative diseases, such as neurodegenerative diseases and dyskinesias, among others.
Inventors:
Johannes Freckner
Liu Ninche
Liu Ninche
Application Number:
JP2002536069A
Publication Date:
April 15, 2004
Filing Date:
October 17, 2001
Export Citation:
Assignee:
Bayer Aktiengesellschaft
International Classes:
A61K31/7088; A61K39/395; A61K45/00; A61K48/00; A61P1/08; A61P7/10; A61P9/10; A61P9/12; A61P9/14; A61P11/06; A61P13/08; A61P17/02; A61P19/10; A61P25/00; A61P25/06; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P35/00; A61P37/08; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/88; C12N15/09; C12N15/60; C12Q1/02; C12Q1/527; C12Q1/68; G01N33/15; G01N33/53; G01N33/566; G01N33/50; (IPC1-7): C12N15/09; A61K31/7088; A61K39/395; A61K45/00; A61K48/00; A61P1/08; A61P7/10; A61P9/10; A61P9/12; A61P9/14; A61P11/06; A61P13/08; A61P17/02; A61P19/10; A61P25/00; A61P25/06; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P35/00; A61P37/08; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/88; C12Q1/02; C12Q1/527; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiromitsu Takayama
Minato Saito
Hiromitsu Takayama
Minato Saito