Title:
個別粒子を生成する方法及び機器
Document Type and Number:
Japanese Patent JP2004511894
Kind Code:
A
Abstract:
A method and apparatus for producing a discrete particle for subsequent analysis (such as mass spectrometry) or manipulation is disclosed. A discrete particle is generated by a particle generator. A net charge is induced onto the particle by an induction electrode. The particle is delivered to a levitation device where it is then electrodynamically levitated. If the particle is a droplet, desolvation will occur, leading to Coloumbic fissioning of the droplet into smaller droplets. The movement of the levitated droplet(s) can be manipulated by an electrode assembly. The droplet(s), and the charge thereon, can be delivered to a mass spectrometer in one aspect of the invention, providing an ion source for mass spectrometry without the detrimental space charge effects of electrospray ionization techniques. In another aspect of the invention, the levitated particle(s) may be controllably and precisely deposited onto a plate for subsequent analysis by matrix assisted laser desorption and ionization mass spectrometry.
More Like This:
Inventors:
Agnes, George
Phone, Xiao
Bogan, Michael
Phone, Xiao
Bogan, Michael
Application Number:
JP2002538445A
Publication Date:
April 15, 2004
Filing Date:
October 23, 2001
Export Citation:
Assignee:
Simon Fraser University
International Classes:
G01N27/62; G21K1/00; G21K1/087; H01J49/04; H01J49/06; H01J49/10; H05H3/04; (IPC1-7): H01J49/10; G01N27/62; G21K1/00; G21K1/087; H01J49/04; H01J49/06
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Makoto Onda