Title:
新規なフィブロネクチンエピトープおよびエピトープに結合可能な蛋白質性分子
Document Type and Number:
Japanese Patent JP2004523230
Kind Code:
A
Abstract:
Means and method for at least partial inhibition of tumor growth are provided. Methods makes use of binding molecules capable of specifically binding to an epitope present on a subset of fibronectin proteins. By providing an individual with a binding molecule of the invention it is possible to interfere with sites of angiogenesis or sites that seen active angiogenesis in the recent past. Through this interference blood flow is at least in part inhibited. Through this inhibition it is possible to at least in part inhibit processes dependent on active angiogenesis in said individual, such as tumor growth.
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Inventors:
Cornelis Adrien Dec Life
Ton logtenberg
Marinus Theodorus Thomas Pennings
Henriette Cristine de Bourg
Ton logtenberg
Marinus Theodorus Thomas Pennings
Henriette Cristine de Bourg
Application Number:
JP2002557966A
Publication Date:
August 05, 2004
Filing Date:
January 18, 2002
Export Citation:
Assignee:
Krusel Holland Bevey
International Classes:
A01H5/00; A01K67/027; A61K38/00; A61K39/395; A61K51/10; A61P35/00; C07K14/78; C07K14/82; C07K16/18; C07K16/30; C07K16/32; C12N5/07; C12N5/078; C12N5/09; C12N5/10; C12N15/09; (IPC1-7): C12N15/09; A01H5/00; A01K67/027; A61K38/00; A61P35/00; C07K16/32; C12N5/06; C12N5/10
Attorney, Agent or Firm:
Kosaku Sugimura