Title:
抗菌活性を有する環状ヘキサペプチド化合物
Document Type and Number:
Japanese Patent JP2004526728
Kind Code:
A
Abstract:
This invention relates to new polypeptide compound represented by the following general formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on beta-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
Inventors:
Ayako Toda
Hiroaki Mizuno
Takahiro Matsuya
Hiroshi Matsuda
Kenji Murano
David Barrett
Takashi Ogino
Keiji Matsuda
Hiroaki Mizuno
Takahiro Matsuya
Hiroshi Matsuda
Kenji Murano
David Barrett
Takashi Ogino
Keiji Matsuda
Application Number:
JP2002571534A
Publication Date:
September 02, 2004
Filing Date:
March 07, 2002
Export Citation:
Assignee:
Fujisawa Pharmaceutical Co., Ltd.
International Classes:
A61P31/00; A61P31/10; C07K1/113; C07K7/50; C07K7/56; A61K38/00; (IPC1-7): C07K7/50; A61K38/00; A61P31/00; A61P31/10; C07K1/113
Attorney, Agent or Firm:
Eiji Tafushi