Title:
2’-ハロ-β-L-アラビノフラノシルヌクレオシドの製造方法
Document Type and Number:
Japanese Patent JP2004526743
Kind Code:
A
Abstract:
The present invention is directed to the process for the preparation of 2'-deoxy-2'-halo-beta-L-arabinofuranosyl nucleosides, and in particular, 2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl thymine (L-FMAU), from L-arabinose, which is commercially available and less expensive than L-ribose or L-xylose, in ten steps. All of the reagents and starting materials are inexpensive and no special equipment is required to carry out the reactions.
Inventors:
Marcos
Application Number:
JP2002577837A
Publication Date:
September 02, 2004
Filing Date:
March 29, 2002
Export Citation:
Assignee:
Triangle Pharmacy Incorporated Incorporated
International Classes:
C07H15/04; C07H19/09; C07H19/06; (IPC1-7): C07H19/09
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura