Title:
抗菌性IB-367ペプチドの経口投与による人工呼吸器関連性肺炎の予防法
Document Type and Number:
Japanese Patent JP2004529095
Kind Code:
A
Abstract:
The present invention provides methods of preventing respiratory infections associated with intubation and/or mechanical ventilation, such as ventilator-associated pneumonia, in intubated patients. The method generally involves topical administration of a composition comprising an IB-367 peptide to the oral cavity of an intubated patient. As IB-367 peptides engender very little resistance, a significant advantage of the invention is that the prophylactic therapy may be applied without having to worry about creating resistant strains of pathogens.
Inventors:
Redman, Rebecca
Hooks, Henry
Hooks, Henry
Application Number:
JP2002563886A
Publication Date:
September 24, 2004
Filing Date:
February 12, 2002
Export Citation:
Assignee:
Intrabiotics Pharmaceuticals, Incorporated
International Classes:
A61K9/08; A61K38/00; A61K38/10; A61K47/10; A61K47/12; A61K47/36; A61K47/38; A61M16/04; A61P11/00; A61P11/12; A61P31/04; (IPC1-7): A61K38/00; A61K9/08; A61K47/10; A61K47/12; A61K47/36; A61K47/38; A61M16/04; A61P11/00; A61P31/04
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama