Title:
逆流症に有効な新規な化合物
Document Type and Number:
Japanese Patent JP2004529982
Kind Code:
A
Abstract:
Novel compounds of formula (I) wherein R1 represents hydrogen; R2 represents hydroxy, fluoro, or an oxo group; R3 represents hydrogen; R4 represents hydrogen; and pharmaceutically acceptable salts, solvates, and the stereoisomers thereof, with the exception of the racemate of (3-amino-2-hydroxypropyl)sulphinic acid. The compounds are useful in therapy, especially for the treatment of reflux disease. The invention is also related to processes for their preparation, intermediates of said process and pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds in therapy
Inventors:
Kevin Fitzpatrick
William Geiss
Anders Lehmann
Gunnel Sunden
Sverkel von Eunye
William Geiss
Anders Lehmann
Gunnel Sunden
Sverkel von Eunye
Application Number:
JP2003503592A
Publication Date:
September 30, 2004
Filing Date:
June 04, 2002
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K31/145; A61K31/185; A61P1/00; A61P1/04; A61P1/08; A61P1/14; A61P11/00; A61P11/06; A61P25/32; A61P25/34; A61P25/36; C07C313/04; C07D277/76; C07D277/74; (IPC1-7): C07C313/04; A61K31/145; A61P1/00; A61P1/04; A61P1/08; A61P1/14; A61P11/00; A61P11/06; A61P25/32; A61P25/34; A61P25/36; C07D277/74; C07D277/76
Attorney, Agent or Firm:
Chika Takagi
Kosuke Nishimura
Junji Yuda
Shoji Miwa
Kosuke Nishimura
Junji Yuda
Shoji Miwa