Title:
リンパ性薬デリバリー系
Document Type and Number:
Japanese Patent JP2004534071
Kind Code:
A
Abstract:
This invention relates to methods of delivering a medium to highly lipophilic drug to the systemic circulation through the lymphatic transport system including the oral administration to a subject in the fasted state of a formulation comprising the lipophilic drug and a component capable of stimulating the production of endogenous lipid, or a component selected from medium to long chain lipids, pharmaceutically acceptable surfactants and combinations thereof, wherein the component is present in an amount sufficient to enhance or promote lymphatic transport of the lipophilic drug, and corresponding methods for avoiding lymphatic transport.
Inventors:
William N. Charman
Christopher JH Porter
Christopher JH Porter
Application Number:
JP2003504942A
Publication Date:
November 11, 2004
Filing Date:
June 14, 2002
Export Citation:
Assignee:
Glaxo Welcome Australia Limited
International Classes:
A61K9/107; A61K9/42; A61K31/137; A61K47/12; A61K9/48; A61K47/14; A61K47/44; A61P33/06; (IPC1-7): A61K9/48; A61K31/137; A61K47/14; A61K47/44
Attorney, Agent or Firm:
Mitsuo Tanaka
Michiko Matsutani
Tadayuki Motoyama
Kenji Tomita
Mina Shiga
Michiko Matsutani
Tadayuki Motoyama
Kenji Tomita
Mina Shiga
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