Title:
閉塞性気道疾患及びその他の炎症性疾患を治療するためのアデノシンA2A受容体アゴニスト及びチオトロピウム又はその誘導体の組合せ
Document Type and Number:
Japanese Patent JP2004534767
Kind Code:
A
Abstract:
A combination of therapeutic agents useful in the treatment of obstructive airways and other inflammatory diseases comprising (i) an adenosine A2A receptor agonist; and (ii) an anti-cholinergic agent, preferably comprising a member selected from the group consisting of tiotropium and derivatives thereof; the combination being therapeutically effective in the treatment of the diseases when administered by inhalation; as well as to a method of treating the obstructive airways and other inflammatory diseases comprising administering separately, simultaneously or sequentially to the mammal by inhalation a therapeutically effective amount of the combination of therapeutic agents; as well as to a pharmaceutical composition comprising a pharmaceutically acceptable carrier together with the combination of therapeutic agents; as well as to a product containing the compounds of the combination for separate, simultaneous or sequential administration by inhalation to a mammal for the treatment of obstructive airways and other inflammatory diseases. It is preferred that the anti-cholinergic agent component be tiotropium bromide.
Inventors:
Yedon Michael
Armstrong Loijin Anne
Watson John W
Armstrong Loijin Anne
Watson John W
Application Number:
JP2002590990A
Publication Date:
November 18, 2004
Filing Date:
May 25, 2002
Export Citation:
Assignee:
Boehringer Ingelheim Pharma Gesellshaft Mitt Beschlenktel Haftung Und Company Comandito Gesellshaft
International Classes:
C07H19/167; A61K9/00; A61K31/46; A61K31/52; A61K31/7076; A61K45/06; A61P11/00; A61P11/06; A61P11/08; A61P29/00; C07D451/12; (IPC1-7): A61K45/06; A61K31/46; A61K31/7076; A61P11/00; A61P11/06; A61P29/00
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama