カテプシン阻害剤としての新しい化合物および組成物

Japanese Patent JP2004535422

A

The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

Michael Graupe
Chiayau Lee
John Oh Link
Sheila Ziffel
Andreas P. Tim
David J. Odus
Scantini Thuray Ratnam

JP2003501840A

November 25, 2004

June 03, 2002

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AXYS PHARMACEUTICALS, INC.

C07D295/18; A61K31/165; A61K31/277; A61K31/341; A61K31/351; A61K31/381; A61K31/397; A61K31/40; A61K31/423; A61K31/4245; A61K31/426; A61K31/427; A61K31/428; A61K31/437; A61K31/4453; A61K31/4468; A61K31/454; A61K31/495; A61K31/5375; A61K31/5377; A61K31/55; A61P1/02; A61P13/12; A61P19/02; A61P21/04; A61P29/00; A61P33/06; A61P35/00; A61P43/00; C07C233/31; C07C255/29; C07C255/44; C07C255/46; C07C271/12; C07C271/16; C07C271/22; C07C271/24; C07C317/44; C07C317/46; C07C317/48; C07D205/04; C07D207/08; C07D207/16; C07D211/66; C07D223/08; C07D223/12; C07D239/08; C07D263/56; C07D271/06; C07D271/10; C07D277/28; C07D277/64; C07D277/82; C07D295/185; C07D295/20; C07D295/205; C07D307/14; C07D309/14; C07D333/24; C07D413/12; C07D413/14; C07D417/12; C07D498/04; (IPC1-7): C07C317/46; A61K31/165; A61K31/277; A61K31/341; A61K31/351; A61K31/381; A61K31/397; A61K31/40; A61K31/423; A61K31/4245; A61K31/426; A61K31/427; A61K31/428; A61K31/437; A61K31/4453; A61K31/4468; A61K31/454; A61K31/495; A61K31/5375; A61K31/5377; A61K31/55; A61P1/02; A61P13/12; A61P19/02; A61P21/04; A61P29/00; A61P33/06; A61P35/00; A61P43/00; C07C255/29; C07C255/44; C07C255/46; C07C271/22; C07C317/44; C07C317/48; C07D205/04; C07D207/16; C07D211/66; C07D223/12; C07D263/56; C07D271/06; C07D271/10; C07D277/28; C07D277/64; C07D295/18; C07D295/20; C07D307/14; C07D309/14; C07D333/24; C07D413/12; C07D413/14; C07D417/12; C07D498/04

Chika Takagi
Kosuke Nishimura
Junji Yuda
Shoji Miwa

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