Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
VLA-1に対する抗体
Document Type and Number:
Japanese Patent JP2004536580
Kind Code:
A
Abstract:
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.

Inventors:
Line, Paul Dee.
Gerber, Ellen Aye.
Saldanha, Jose W.
Carpsus, michael
Application Number:
JP2002582193A
Publication Date:
December 09, 2004
Filing Date:
April 12, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
Biogen Idec MA Inc.
International Classes:
A61K39/395; A61K49/16; A61P29/00; A61P37/00; C07H21/04; C07K16/18; C07K16/24; C07K16/28; G01N33/50; C07K16/46; C12N1/00; C12N5/10; C12N5/12; C12N5/20; C12N5/22; C12N9/00; C12N15/07; C12N15/09; C12N15/11; C12N15/13; G01N33/15; G01N33/53; G01N33/543; G01N33/567; G01N33/577; G06F17/00; G06F17/30; H04N9/64; H04N13/02; H04N15/00; C12N; (IPC1-7): C12N15/09; A61K39/395; A61P29/00; C07K16/28; C12N5/10; G06F17/30
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita