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Title:
分画細胞計数方法ならびにそれを実行するための関連する装置およびソフトウェア
Document Type and Number:
Japanese Patent JP2005502369
Kind Code:
A
Abstract:
The present invention provides an optical method, system and software for imaging cells, in particular blood cells. In one embodiment, laboratory samples containing blood cells are deposited onto bio-discs, which are specially manufactured discs with mixing chambers that contain specific antigens to lock down various components of the blood cells. Once in the optical drive, the disc is spun and the samples and antigens are mixed with other solutions. Electromagnetic beams are then directed at the bio-disc to interact with the samples at specific capture zones and the resulting beams are collected by a detector. The information contained in the beams is then sent to a processor that produces a digital image. Various image processing methods such as binarization, background uniformization, normalization and filtering are performed to enhance cells in the investigational data for accurate counting. Other techniques are designed to correct for irregularities such as bubbles and dim cells.

Inventors:
Matobib, Mikhail
Pal, Andrew Attila
Application Number:
JP2003527562A
Publication Date:
January 27, 2005
Filing Date:
September 11, 2002
Export Citation:
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Assignee:
Burstein Technologies, Incorporated
International Classes:
G06M11/02; C12Q1/06; G01N15/00; G01N15/14; G01N21/03; G01N33/48; G01N33/483; G01N33/50; G01N35/00; G06T1/00; (IPC1-7): C12Q1/06; G01N15/00; G01N21/03; G01N33/48; G01N33/483; G06M11/02; G06T1/00
Domestic Patent References:
JPH05215750A1993-08-24
JPH03255365A1991-11-14
JPH11133021A1999-05-21
JPH09503868A1997-04-15
JPS5952359A1984-03-26
JPH10275150A1998-10-13
JPH09173300A1997-07-08
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Yutaka Nagata
Tsutomu Toyama