Title:
新規なシアノ置換されたジヒドロピリミジン化合物および疾患を治療する用途
Document Type and Number:
Japanese Patent JP2005504725
Kind Code:
A
Abstract:
The present invention provides compounds of formula Iand pharmaceutically acceptable salts thereof.The formula I compounds induce mitotic arrest thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inducing mitotic arrest.
Inventors:
Spencer David Kimball
Louis Jay Lombard
David B Rawlins
Xiao Hai-Yoon
Robert Joseph Schmidt
David Kent Williams
Louis Jay Lombard
David B Rawlins
Xiao Hai-Yoon
Robert Joseph Schmidt
David Kent Williams
Application Number:
JP2002577776A
Publication Date:
February 17, 2005
Filing Date:
March 26, 2002
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/505; A61K31/506; A61K31/513; A61P9/14; A61P35/00; C07D211/90; C07D239/22; C07D239/40; C07D239/42; C07D401/04; C07D401/10; C07D239/36; C07D403/10; C07D403/12; C07D405/04; C07D409/04; C07D409/06; C07D409/10; C07D413/04; C07D413/10; C07D413/14; C07D417/04; (IPC1-7): C07D239/36; A61K31/505; A61K31/506; A61K31/513; A61P35/00; C07D239/40; C07D405/04; C07D409/04; C07D413/04; C07D413/14; C07D417/04
Attorney, Agent or Firm:
Kyousei Tamura
Nagatoshi Shinagawa
Nagatoshi Shinagawa
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